亚洲免费网站观看视频-成人色视频-99国产精品欧美一区二区三区-一本色道婷婷久久欧美-麻豆国产成人av高清在线观看

您好,歡迎進入上海力敏實業有限公司網站!
一鍵分享網站到:
您現在的位置:首頁 >> 產品中心 >> 生化試劑、抗體、血清 >> 細胞因子 >> 3214-EG-100R&D代理Recombinant Rat EGF重組鼠表皮生長因子RD供應*

R&D代理Recombinant Rat EGF重組鼠表皮生長因子RD供應*

  • 更新時間:  2023-07-25
  • 產品型號:  3214-EG-100
  • 簡單描述
  • 此類產品還有人的表皮細胞生長因子,上海利民實業有限公司是華東區RD代理,咨詢產品 纖細說明書見詳細介紹
詳細介紹

DESCRIPTION
Source E. coliderived
Asn974Arg1026,
with an Nterminal
Met
Accession # P07522
Nterminal
Sequence
Analysis
Met
Predicted Molecular
Mass
6.3 kDa
SPECIFICATIONS
Activity Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. Rubin, J.S. et al. (1991) Proc. Natl. Acad. Sci. USA
88:415.
The ED50 for this effect is typically 1060
pg/mL.
Endotoxin Level <1.0 EU per 1 μg of the protein by the LAL method.
Purity >97%, by SDSPAGE
under reducing conditions and visualized by silver stain.
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. See Certificate of Analysis for details.
PREPARATION AND STORAGE
Reconstitution Reconstitute at 100 μg/mL in sterile 10 mM Acetic Acid containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediay at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freezethaw
cycles.
l 12 months from date of receipt, 20
to 70
°C as supplied.
l 1 month, 2 to 8 °C under sterile conditions after reconstitution.
l 3 months, 20
to 70
°C under sterile conditions after reconstitution.
BACKGROUND
Epidermal growth factor (EGF) is the founding member of the EGF family that also includes TGFα,
amphiregulin (AR), betacellulin (BTC), epiregulin (EPR), heparinbinding
EGFlike
growth factor(HBEGF),
epigen, and the neuregulins (NRG)1
through 6
(1). Members of the EGF family share a structural motif, the EGFlike
domain, which is characterized by three intramolecular disulfide bonds that are formed by six similarly spaced conserved cysteine residues (2). All EGF family
members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are
released from the cell surface by regulated proteolysis (1). The 1133 amino acid (aa) rat EGF precursor contains nine EGF domains and nine LDLR class B repeats.
The mature protein consists of 53 aa and is generated by proteolytic excision of the EGF domain proximal to the transmembrane region (3). Mature rat EGF shares
70% and 77% aa sequence identity with mature human and mouse EGF, respectively. EGF is present in various body fluids, including blood, milk, urine, saliva,
seminal fluid, pancreatic juice, cerebrospinal fluid, and amniotic fluid (4). Four ErbB (HER) family receptor tyrosine kinases including EGFR/ErbB1, ErbB2, ErbB3 and
ErbB4, mediate responses to EGF family members (5). These receptors undergo a complex pattern of ligand induced homoor
heterodimerization
to transduce EGF
family signals (6, 7). EGF binds ErbB1 and depending on the context, induces the formation of homodimers or heterodimers containing ErbB2. Dimerization results in
autophosphorylation of the receptor at specific tyrosine residues to create docking sites for a variety of signaling molecules (5, 8). Biological activities ascribed to
EGF include epithelial development, angiogenesis, inhibition of gastric acid secretion, fibroblast proliferation, and colony formation of epidermal cells in culture.
References:
1. Harris, R.C. et al. (2003) Exp. Cell Res. 284:2.
2. Carpenter, G. and Cohen, S. (1990) J. Biol. Chem. 265:7709.
3. Saggi, S.J. et al. (1992) DNA Cell Biol. 11:481.
4. Carpenter, G. and Zendegui, J.G. (1986) Exp. Cell Res. 164:1.
5. Jorissen, R.N. et al. (2003) Exp. Cell Res. 284:31.
6. Gamett, D.C. et al. (1997) J. Biol. Chem. 272:12052.
7. Qian, X. et al. (1994) Proc. Natl. Acad. Sci. 91:1500.
8. Qian, X. et al. (1999) J. Biol. Chem. 274:574.
Recombinant Rat EGF
Catalog Number: 3214-EG
www.


留言框

  • 產品:

  • 您的單位:

  • 您的姓名:

  • 聯系電話:

  • 常用郵箱:

  • 省份:

  • 詳細地址:

  • 補充說明:

  • 驗證碼:

    請輸入計算結果(填寫阿拉伯數字),如:三加四=7
主站蜘蛛池模板: 国产做爰xxxⅹ久久久精华液| 四十如虎的丰满熟妇啪啪| 四川丰满妇女毛片四川话| 中文无码日韩欧| 丰满日韩放荡少妇无码视频| 免费无码无遮挡裸体视频在线观看| 精品国产一区二区三区不卡| 国产无遮挡又爽又黄大胸免费| 午夜影视免费| 丰满人妻熟妇乱又伦精品视| 国产精品另类激情久久久免费| 疯狂做受xxxx高潮视频免费| 欧美日产亚洲国产精品| 日本添下边视频全过程| 亚洲一本到无码av中文字幕| 无码人妻精品一区二区蜜桃百度| 超碰97人人做人人爱网站| 成年无码按摩av片在线观看| 亚洲综合图片区自拍区| 亚洲国产日韩a在线乱码| 女人天堂一区二区三区| 亚洲中文无码av永久不收费| 国产精品爽爽v在线观看无码| 小说区 图片区色 综合区| 亚洲精品无播放器在线播放| 欧美黑人巨大xxxxx| 国产精品国产三级国产aⅴ下载 | 久久天天躁狠狠躁夜夜躁2012| 亚洲制服丝袜一区二区三区| 国产高清无密码一区二区三区| 国产欧美日韩一区二区加勒比| 玩弄中年熟妇正在播放| 久久精品国产色蜜蜜麻豆| 国精产品自偷自偷综合下载 | 国产精品久久久久野外| 国产在线精品成人一区二区| 岛国精品一区免费视频在线观看 | 亚洲欧美综合国产精品二区| 午夜精品久久久久久久久| 男人把女人桶到爽免费应用| 日韩v亚洲v欧美v精品综合|